Porphyria — Web Search Results on TateSearch

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Porphyria

Wikipedia

Porphyria is a group of disorders in which substances called porphyrins build up in the body, adversely affecting the skin or nervous system. The types that affect the nervous system are also known as acute porphyria, as symptoms are rapid in onset and short in duration. Symptoms of an attack include abdominal pain, chest pain, vomiting, confusion, constipation, fever, high blood pressure, and high heart rate. The attacks usually last for days to weeks. Complications may include paralysis, low blood sodium levels, and seizures. Attacks may be triggered by alcohol, smoking, hormonal changes, fasting, stress, or certain medications. If the skin is affected, blisters or itching may occur with sunlight exposure. Most types of porphyria are inherited from one or both of a person's parents and are due to a mutation in one of the genes that make heme. They may be inherited in an autosomal dominant, autosomal recessive, or X-linked dominant manner.

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Pronunciation or

Specialty Hematology, dermatology, neurology

Symptoms Depending on subtype—abdominal pain, chest pain, vomiting, confusion, constipation, fever, seizures, blisters with sunlight

Usual onset Recurrent attacks that last days to weeks

Causes Usually genetic

Diagnostic method Blood, urine, and stool tests, genetic testing

Differential diagnosis Lead poisoning, alcoholic liver disease

Treatment Depends on type and symptoms

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Porphyria — Web Search Results on TateSearch

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